Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Neurog3  neurogenin 3   (Synonyms: Atoh5, bHLHa7, Math4B, ngn3)
Results	Reference
1	J:287136 Aslanpour S, Han S, Schuurmans C, Kurrasch DM, Neurog2 Acts as a Classical Proneural Gene in the Ventromedial Hypothalamus and Is Required for the Early Phase of Neurogenesis. J Neurosci. 2020 Apr 29;40(18):3549-3563
1	J:268361 Byrnes LE, Wong DM, Subramaniam M, Meyer NP, Gilchrist CL, Knox SM, Tward AD, Ye CJ, Sneddon JB, Lineage dynamics of murine pancreatic development at single-cell resolution. Nat Commun. 2018 Sep 25;9(1):3922
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1	J:168537 Gouzi M, Kim YH, Katsumoto K, Johansson K, Grapin-Botton A, Neurogenin3 initiates stepwise delamination of differentiating endocrine cells during pancreas development. Dev Dyn. 2011 Mar;240(3):589-604
1	J:98770 Henseleit KD, Nelson SB, Kuhlbrodt K, Hennings JC, Ericson J, Sander M, NKX6 transcription factor activity is required for {alpha}- and {beta}-cell development in the pancreas. Development. 2005 Jul;132(13):3139-49
1*	J:139177 Hoffman BG, Zavaglia B, Witzsche J, Ruiz de Algara T, Beach M, Hoodless PA, Jones SJ, Marra MA, Helgason CD, Identification of transcripts with enriched expression in the developing and adult pancreas. Genome Biol. 2008;9(6):R99
1	J:61566 Huang HP, Liu M, El-Hodiri HM, Chu K, Jamrich M, Tsai MJ, Regulation of the pancreatic islet-specific gene BETA2 (neuroD) by neurogenin 3. Mol Cell Biol. 2000 May;20(9):3292-307
1	J:62595 Jacquemin P, Durviaux SM, Jensen J, Godfraind C, Gradwohl G, Guillemot F, Madsen OD, Carmeliet P, Dewerchin M, Collen D, Rousseau GG, Lemaigre FP, Transcription factor hepatocyte nuclear factor 6 regulates pancreatic endocrine cell differentiation and controls expression of the proendocrine gene ngn3. Mol Cell Biol. 2000 Jun;20(12):4445-54
1	J:80672 Jenny M, Uhl C, Roche C, Duluc I, Guillermin V, Guillemot F, Jensen J, Kedinger M, Gradwohl G, Neurogenin3 is differentially required for endocrine cell fate specification in the intestinal and gastric epithelium. EMBO J. 2002 Dec 2;21(23):6338-47
1	J:75811 Kim SK, Selleri L, Lee JS, Zhang AY, Gu X, Jacobs Y, Cleary ML, Pbx1 inactivation disrupts pancreas development and in Ipf1-deficient mice promotes diabetes mellitus. Nat Genet. 2002 Apr;30(4):430-5
1	J:138261 Kokubu H, Ohtsuka T, Kageyama R, Mash1 is required for neuroendocrine cell development in the glandular stomach. Genes Cells. 2008 Jan;13(1):41-51
1	J:335488 Manea T, Nelson JK, Garrone CM, Hansson K, Evans I, Behrens A, Sancho R, USP7 controls NGN3 stability and pancreatic endocrine lineage development. Nat Commun. 2023 Apr 28;14(1):2457
1	J:152848 Martinez-Romero C, Rooman I, Skoudy A, Guerra C, Molero X, Gonzalez A, Iglesias M, Lobato T, Bosch A, Barbacid M, Real FX, Hernandez-Munoz I, The epigenetic regulators Bmi1 and Ring1B are differentially regulated in pancreatitis and pancreatic ductal adenocarcinoma. J Pathol. 2009 Oct;219(2):205-13
1	J:125691 Masui T, Long Q, Beres TM, Magnuson MA, Macdonald RJ, Early pancreatic development requires the vertebrate Suppressor of Hairless (RBPJ) in the PTF1 bHLH complex. Genes Dev. 2007 Oct 15;21(20):2629-43
1	J:106988 Mellitzer G, Bonne S, Luco RF, Van De Casteele M, Lenne-Samuel N, Collombat P, Mansouri A, Lee J, Lan M, Pipeleers D, Nielsen FC, Ferrer J, Gradwohl G, Heimberg H, IA1 is NGN3-dependent and essential for differentiation of the endocrine pancreas. EMBO J. 2006 Mar 22;25(6):1344-52
1	J:336513 Patzek S, Liu Z, de la O S, Chang S, Byrnes LE, Zhang X, Ornitz DM, Sneddon JB, Loss of Fgf9 in mice leads to pancreatic hypoplasia and asplenia. iScience. 2023 Apr 21;26(4):106500
1*	J:82083 Pulkkinen MA, Spencer-Dene B, Dickson C, Otonkoski T, The IIIb isoform of fibroblast growth factor receptor 2 is required for proper growth and branching of pancreatic ductal epithelium but not for differentiation of exocrine or endocrine cells. Mech Dev. 2003 Feb;120(2):167-75
1*	J:155929 Soyer J, Flasse L, Raffelsberger W, Beucher A, Orvain C, Peers B, Ravassard P, Vermot J, Voz ML, Mellitzer G, Gradwohl G, Rfx6 is an Ngn3-dependent winged helix transcription factor required for pancreatic islet cell development. Development. 2010 Jan;137(2):203-12
1	J:185653 Tsai HH, Li H, Fuentealba LC, Molofsky AV, Taveira-Marques R, Zhuang H, Tenney A, Murnen AT, Fancy SP, Merkle F, Kessaris N, Alvarez-Buylla A, Richardson WD, Rowitch DH, Regional astrocyte allocation regulates CNS synaptogenesis and repair. Science. 2012 Jul 20;337(6092):358-62
1*	J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
1	J:86239 Yoshida T, Tokunaga A, Nakao K, Okano H, Distinct expression patterns of splicing isoforms of mNumb in the endocrine lineage of developing pancreas. Differentiation. 2003 Oct;71(8):486-495
1	J:123923 Zhou Q, Law AC, Rajagopal J, Anderson WJ, Gray PA, Melton DA, A multipotent progenitor domain guides pancreatic organogenesis. Dev Cell. 2007 Jul;13(1):103-14